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The Raelian Movement
for those who are not afraid of the future : http://www.rael.org
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Higher serum selenium levels linked with lower prostate cancer risk
http://www.lef.org/newsletter/2010/0924_Higher-Serum-Selenium-Levels-Linked-with-Lower-Prostate-Cancer-Risk.htm?source=eNewsLetter2010Wk39-2&key=Archive
An article published online on September 17, 2010 in the journal
Cancer Epidemiology, Biomarkers & Prevention reports a benefit between
higher levels of the mineral selenium and a reduced risk of prostate
cancer. The finding contradicts the conclusion of other research which
failed to determine a protective benefit for selenium in the disease.
In their introduction, the authors remark that "Increased intake of
selenium has been suggested to have anticarcinogenic effects and
numerous mechanisms have been proposed to explain this property:
reduction of DNA damage, oxidative stress or inflammation; also,
induction of phase II enzymes, enhancement of immune response,
inhibition of cell cycle and angiogenesis and induction of apoptosis .
. . Intervention studies in humans have shown that supplementation of
selenium leads to an increase in concentration and/or activity of
circulating selenoproteins, such as selenoprotein P (SePP) or
glutathione peroxidases (GPx), and plasma SePP and GPx3 represent
common markers of selenium status. Since GPx are important components
of the redox control system in humans, reduction of cellular oxidative
stress and subsequent DNA damage could be a major mechanism to explain
t he anticancer effects of selenium."
Prostate cancer overview
Measures to prevent prostate cancer (PC) must be a routine part of the
counsel that general practitioners and internists give their patients.
Selenium intake of at least 200 mcg a day should be a consideration in
the prevention of PC. Low plasma selenium is associated with a four-
to fivefold increased risk of PC. In addition, levels of plasma
selenium also decrease with age, resulting in middle-aged to older men
being at a higher risk for low selenium levels. Ideally, baseline
levels of selenium should be obtained before beginning routine
selenium supplementation. It would make sense to begin such a
micronutrient and mineral assessment at age 25 and perhaps every 10
years thereafter.
Selenium also has been shown to have a significant antineoplastic
effect on breast, lung, liver, and small intestinal tumor cells.
Supplementation with selenium enhanced the chemotherapeutic effects of
Taxol (paclitaxel) and Adriamycin (doxorubicin) in these cells beyond
that seen when the chemotherapeutic drugs were used alone. In studies
of the PC cell lines LNCaP and PC-3, the addition of Taxol or
Adriamycin, in combination with selenium, caused small but significant
inhibition of the PC cell growth. In the cited studies, the optimal
inhibition of tumor growth occurred when the plasma selenium level was
between 4 -40 ng/mL after 72 hours of treatment.
A large-scale study of almost 11,000 men in Maryland showed that the
protective effects of high selenium levels, and similarly that of the
alpha-tocopherol isomer of vitamin E, were only observed when the
concentrations of the gamma tocopherol isomer of vitamin E were also
high. In this study, the risk of PC declined with increasing
concentrations of alpha-tocopherol, with the highest concentration
associated with a 68% PC risk reduction. For gamma-tocopherol, men
with levels in the highest fifth of the distribution had a fivefold
greater reduction in the risk of developing PC than men in the lowest
fifth (p = .002). The observed interaction between alpha-tocopherol,
gamma-tocopherol, and selenium suggested that combined alpha- and
gamma-tocopherol supplements, used in conjunction with selenium,
should be considered in future PC prevention trials.
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WARNING FROM RAEL: For those who don't use their intelligence at its full
capacity, the label "selected by RAEL" on some articles does not mean that I
agree with their content or support it. "Selected by RAEL" means that I believe
it is important for the people of this planet to know about what people think or
do, even when what they think or do is completely stupid and against our
philosophy. When I selected articles in the past about stupid Christian
fundamentalists in America praying for rain, I am sure no Rael-Science reader
was stupid enough to believe that I was supporting praying to change the
weather. So, when I select articles which are in favor of drugs, anti-semitic,
anti-Jewish, racist, revisionist, or inciting hatred against any group or
religion, or any other stupid article, it does not mean that I support them. It
just means that it is important for all human beings to know about them. Common
sense, which is usually very good among our readers, is good enough to
understand that. When, like in the recent articles on drug decriminalization, it
is necessary to make it clearer, I add a comment, which in this case was very
clear: I support decriminalizing all drugs, as it is stupid to throw depressed
and sad people (as only depressed and sad people use drugs) in prison and ruin
their life with a criminal record. That does not mean that there is any change
to the Message which says clearly that we must not use any drug except for
medical purposes. The same applies to the freedom of expression which must be
absolute. That does not mean again of course that I agree with anti-Jews,
antisemites, racists of any kind or anti-Raelians. But by knowing your enemies
or the enemies of your values, you are better equipped to fight them. With love
and respect of course, and with the wonderful sentence of the French philosopher
Voltaire in mind: "I disapprove of what you say, but I will defend to the death
your right to say it".
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"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
There is nothing glorious about what our ancestors call history,
it is simply a succession of mistakes, intolerances and violations.
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
Rael
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