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Study reveals new potential benefit of testosterone: Could HRT for men cut the risk of heart disease?
http://www.dailymail.co.uk/health/article-1321983/Could-HRT-men-cut-risk-heart-disease.html
By Jenny Hope
Last updated at 3:47 AM on 20th October 2010
Men with low testosterone are at greater risk of dying prematurely from heart disease and other causes, researchers warn.
They found almost twice as many men with low levels of the male hormone died, compared to those with normal levels.
And their research suggests that many men at risk of heart disease would benefit from testosterone replacement therapy such as patches, injections and gels.
High risk: The study shows that men with lower levels of testosterone had a higher risk of suffering a heart attack
The experts tracked the progress of almost 1,000 men with coronary heart disease for around seven years.
Low testosterone affected one in four and was an independent risk factor for early death.
Professor Kevin Channer, of Sheffield's Royal Hallamshire Hospital department of cardiology, said the finding refutes fears that testosterone might actually cause heart problems.
Although high doses of testosterone in anabolic steroids used by bodybuilders are known to damage health, the latest study suggests deficiency can be just as harmful. Professor Channer said: 'There is ongoing debate over the risk-benefit ratio of testosterone replacement in patients who are deficient, and there is still concern among doctors it might increase the risk of vascular disease.
'Short-term studies show improvements in cardiovascular health, even in men with lower than average testosterone levels – and men feel much better when they are taking it.'
Testosterone is a key male hormone responsible for sex drive, sperm production and muscle tone but its production declines gradually in middle age.
Some doctors dismiss the fashion of men taking it to ward off ageing and increase their sex drive. But there has been a huge increase in demand for treatment as more than a million men in the UK have some kind of problem with erectile dysfunction.
Patches, injections, skin gels, creams and oral capsules are all used to treat testosterone deficiency, many by private clinics offering a male menopause service. Testosterone products are wrongly regarded as 'sex aids' although they can boost libido and improve a man's response to drugs such as Viagra.
In the latest study, 930 men with coronary heart disease who were referred to a specialist heart centre between 2000 and 2002 had their testosterone levels checked and health monitored for seven years.
Those most at risk had abnormally low levels – known as hypogonadism – rather than the natural reduction which occurs with ageing.
During the monitoring period almost twice as many men with low testosterone – one in five – died as did those with normal levels – one in eight – says a report in the medical journal Heart.
Men at high risk of diabetes and heart disease may stand to gain most from testosterone replacement, said Professor Channer.
'Physiological testosterone replacement is an inexpensive and well-tolerated therapy but does require careful monitoring.'
But there are risks to replacement therapy including prostate cancer, claims Dr Ronald Ma of the Chinese University of Hong Kong in an accompanying editorial.
A recent trial of 800 men over 50 at the University of California San Diego showed having low testosterone raises the risk of death from heart disease.
Read more: http://www.dailymail.co.uk/health/article-1321983/Could-HRT-men-cut-risk-heart-disease.html#ixzz12shoQ0hJWARNING FROM RAEL: For those who don't use their intelligence at its full
capacity, the label "selected by RAEL" on some articles does not mean that I
agree with their content or support it. "Selected by RAEL" means that I believe
it is important for the people of this planet to know about what people think or
do, even when what they think or do is completely stupid and against our
philosophy. When I selected articles in the past about stupid Christian
fundamentalists in America praying for rain, I am sure no Rael-Science reader
was stupid enough to believe that I was supporting praying to change the
weather. So, when I select articles which are in favor of drugs, anti-semitic,
anti-Jewish, racist, revisionist, or inciting hatred against any group or
religion, or any other stupid article, it does not mean that I support them. It
just means that it is important for all human beings to know about them. Common
sense, which is usually very good among our readers, is good enough to
understand that. When, like in the recent articles on drug decriminalization, it
is necessary to make it clearer, I add a comment, which in this case was very
clear: I support decriminalizing all drugs, as it is stupid to throw depressed
and sad people (as only depressed and sad people use drugs) in prison and ruin
their life with a criminal record. That does not mean that there is any change
to the Message which says clearly that we must not use any drug except for
medical purposes. The same applies to the freedom of expression which must be
absolute. That does not mean again of course that I agree with anti-Jews,
antisemites, racists of any kind or anti-Raelians. But by knowing your enemies
or the enemies of your values, you are better equipped to fight them. With love
and respect of course, and with the wonderful sentence of the French philosopher
Voltaire in mind: "I disapprove of what you say, but I will defend to the death
your right to say it".
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"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
There is nothing glorious about what our ancestors call history,
it is simply a succession of mistakes, intolerances and violations.
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
Rael
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