The Raelian Movement
for those who are not afraid of the future : http://www.rael.org
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Surprise: Scientists Discover That Inflammation Helps to Heal Wounds
http://www.sciencedaily.com/releases/2010/10/101004130105.htm
ScienceDaily (Oct. 5, 2010) — A new research study published in The
FASEB Journal may change how sports injuries involving muscle tissue
are treated, as well as how much patient monitoring is necessary when
potent anti-inflammatory drugs are prescribed for a long time. That's
because the study shows for the first time that inflammation actually
helps to heal damaged muscle tissue, turning conventional wisdom on
its head that inflammation must be largely controlled to encourage
healing.
These findings could lead to new therapies for acute muscle injuries
caused by trauma, chemicals, infections, freeze damage, and exposure
to medications which cause muscle damage as a side effect. In
addition, these findings suggest that existing and future therapies
used to combat inflammation should be closely examined to ensure that
the benefits of inflammation are not eliminated.
"We hope that our findings stimulate further research to dissect
different roles played by tissue inflammation in clinical settings, so
we can utilize the positive effects and control the negative effects
of tissue inflammation," said Lan Zhou, M.D., Ph.D., a researcher
involved in the work from the Neuroinflammation Research
Center/Department of Neurosciences/Lerner Research Institute at the
Cleveland Clinic in Ohio.
Zhou and colleagues found that the presence of inflammatory cells
(macrophages) in acute muscle injury produce a high level of a growth
factor called insulin-like growth factor-1 (IGF-1) which significantly
increases the rate of muscle regeneration. The research report shows
that muscle inflammatory cells produce the highest levels of IGF-1,
which improves muscle injury repair. To reach this conclusion, the
researchers studied two groups of mice. The first group of mice was
genetically altered so they could not mount inflammatory responses to
acute injury. The second group of mice was normal. Each group
experienced muscle injury induced by barium chloride. The muscle
injury in the first group of mice did not heal, but in the second
group, their bodies repaired the injury. Further analysis showed that
macrophages within injured muscles in the second group of mice
produced a high level of IGF-1, leading to significantly improved
muscle repair.
"For wounds to heal we need controlled inflammation, not too much, and
not too little," said Gerald Weissmann, M.D., Editor-in-Chief of The
FASEB Journal, "It's been known for a long time that excess
anti-inflammatory medication, such as cortisone, slows wound healing.
This study goes a long way to telling us why: insulin-like growth
factor and other materials released by inflammatory cells helps wound
to heal."
Story Source:
The above story is reprinted (with editorial adaptations by
ScienceDaily staff) from materials provided by Federation of American
Societies for Experimental Biology, via EurekAlert!, a service of
AAAS.
Journal Reference:
1. H. Lu, D. Huang, N. Saederup, I. F. Charo, R. M. Ransohoff, L.
Zhou. Macrophages recruited via CCR2 produce insulin-like growth
factor-1 to repair acute skeletal muscle injury. The FASEB Journal,
2010; DOI: 10.1096/fj.10-171579
------------------------------------
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
There is nothing glorious about what our ancestors call history,
it is simply a succession of mistakes, intolerances and violations.
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
Rael
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
-----------------------------------------------------------------
Tell your friends who love scientific news that they can
subscribe to this list !!
They can do it by sending a blank email to:
rael-science-select-subscribe@yahoogroups.com
It's free !
-----------------------------------------------------------------
To unsubscribe, send an email to:
rael-science-select-unsubscribe@yahoogroups.com
-----------------------------------------------------------------
To change your e-mail address, unsubscribe from the old address and subscribe from the new address (see above).
-----------------------------------------------------------------
Yahoo! Groups Links
<*> To visit your group on the web, go to:
http://groups.yahoo.com/group/rael-science-select/
<*> Your email settings:
Individual Email | Traditional
<*> To change settings online go to:
http://groups.yahoo.com/group/rael-science-select/join
(Yahoo! ID required)
<*> To change settings via email:
rael-science-select-digest@yahoogroups.com
rael-science-select-fullfeatured@yahoogroups.com
<*> To unsubscribe from this group, send an email to:
rael-science-select-unsubscribe@yahoogroups.com
<*> Your use of Yahoo! Groups is subject to:
http://docs.yahoo.com/info/terms/
0 comments:
Post a Comment