The Raelian Movement
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Technique to Reattach Teeth Using Stem Cells Developed
http://www.sciencedaily.com/releases/2010/09/100929123630.htm
ScienceDaily (Sep. 30, 2010) — A new approach to anchor teeth back in
the jaw using stem cells has been developed and successfully tested in
the laboratory for the first time by researchers at the University of
Illinois at Chicago.
The new strategy represents a potential major advance in the battle
against gum disease, a serious infection that eventually leads to
tooth loss. About 80 percent of U.S. adults suffer from gum disease,
according to the National Institute of Dental and Craniofacial
Research.
Researchers in UIC's Brodie Laboratory for Craniofacial Genetics used
stem cells obtained from the periodontal ligament of molars extracted
from mice, expanded them in an incubator, and then seeded them on
barren rat molars. The stem cell-treated molars were reinserted into
the tooth sockets of rats.
After two and four months, the stem cells aligned and formed new
fibrous attachments between the tooth and bone, firmly attaching the
replanted tooth into the animal's mouth, said Smit Dangaria, a
bioengineering doctoral candidate who conducted the research. Tissue
sections showed that the replanted tooth was surrounded by newly
formed, functional periodontal ligament fibers and new cementum, the
essential ingredients of a healthy tooth attachment.
In contrast, tooth molars that were replanted without new
stem/progenitor cells were either lost or loosely attached and were
resorbed, Dangaria said.
The study, published in an online issue of the journal Tissue
Engineering, was funded through a grant by the National Institutes of
Health.
Dangaria said the natural surface of the tooth played an essential
role in the study.
"Our research uncovered the code required to reattach teeth -- a
combination of natural tooth root surface structure together with
periodontal progenitor cells," he said.
To verify that the ligament was formed by the transplanted stem cells
and not by the animal's own cells, stem cells were labeled with green
fluorescent protein prior to seeding them on the molars and
re-inserting the teeth into the animal's mouth, Dangaria said.
According to Tom Diekwisch, director of the Brodie Laboratory, who is
senior author on the paper, this is the first progenitor cell-based
regeneration of a complete periodontal ligament in which a functional
tooth was attached.
"Our strategy could be used for replanting teeth that were lost due to
trauma or as a novel approach for tooth replacement using tooth-shaped
replicas," said Diekwisch, who is also professor and head of oral
biology.
Assisting Dangaria and Diekwisch were Yoshihiro Ito and Xianghong Luan
of UIC's Brodie Laboratory; Leilei Yin of the University of Illinois
at Urbana-Champaign; and Giovanni Valdre of the University of Bologna,
Italy.
Story Source:
The above story is reprinted (with editorial adaptations by
ScienceDaily staff) from materials provided by University of Illinois
at Chicago.
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"Ethics" is simply a last-gasp attempt by deist conservatives and
orthodox dogmatics to keep humanity in ignorance and obscurantism,
through the well tried fermentation of fear, the fear of science and
new technologies.
There is nothing glorious about what our ancestors call history,
it is simply a succession of mistakes, intolerances and violations.
On the contrary, let us embrace Science and the new technologies
unfettered, for it is these which will liberate mankind from the
myth of god, and free us from our age old fears, from disease,
death and the sweat of labour.
Rael
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